Caloric Restriction May Unlock Epigenetic Secrets to Longevity
“To lengthen thy life, lessen thy meals.” – Benjamin Franklin. For millennia, fasting has been lauded as a path to discipline, purity, longevity, and mental acuity. While Franklin may not have always heeded his own advice, his contention, one shared by many cultures throughout history, is now backed by over eight decades of scientific research. Caloric restriction (CR) is the most thoroughly studied longevity intervention to date. In humans and animals, it consistently increases lifespan and healthspan (McDonald, 2010). Any [more…]