Epigenetic Changes Dictate Cancer’s Course

November 29, 2023 Natalie Crowley

Understanding the intricate interplay between genetics and cancer progression has long captivated the scientific community. While genetic mutations have been the main focal point in oncology, recent strides have illuminated the profound influence of epigenetic modifications in the development of cancer. In a recent study published in the journal Nature, Dr. Eduard Porta from the Josep Carreras Leukaemia Research Institute and his team have shed light on the pivotal role that epigenetics plays in steering cells on their journey from [more…]

Unveiling the Epigenetic Impact of Formaldehyde: A Hazardous Environmental Pollutant

November 14, 2023 Natalie Crowley

A global team of researchers has unveiled a groundbreaking revelation regarding formaldehyde, a pervasive environmental pollutant and a common metabolite in the human body. Contrary to its previous characterization solely as a DNA mutagen, formaldehyde has been found to disrupt the epigenetic programming of cells, establishing a deeper link with cancer. Dr. Lucas Pontel, group leader at the Josep Carreras Leukaemia Research Institute, and Dr. Manel Esteller, group leader and director of the institution, collaborated on the published paper in [more…]

AI Detects Disease Clues from DNA Methylation Data

November 1, 2023 Natalie Crowley

Artificial intelligence (AI) holds immense potential to transform healthcare by unraveling intricate patterns within complex biological data, laying the foundation for personalized medical solutions. Researchers at Link√∂ping University in Sweden have pioneered an AI-driven method to analyze epigenetic data, with wide-ranging applications in medicine and biology. Their advanced models not only accurately estimate individuals’ chronological age but also discern their smoking history. In the realm of genetics, numerous factors come into play, dictating which genes are activated or deactivated at [more…]

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