Epigenetic study uncovers non-coding Alzheimer’s-related genetic variants

October 17, 2023 Natalie Crowley

In the ongoing pursuit of understanding Alzheimer’s disease (AD), scientists are taking a closer look at the genetic landscape. Their investigation has revealed thousands of genetic variants linked to AD, many of which were once overlooked as non-coding regions of the genome. Recent advancements in the field of epigenetics have illuminated the critical role these non-coding variants play in gene regulation. However, how these gene changes affect Alzheimer’s risk and brain cells is still unclear. Researchers from the University of [more…]

Epigenetic Impact of Historical Trauma on Alaska Native Communities

October 3, 2023 Natalie Crowley

The history of Indigenous peoples in North America has been marked by enduring challenges, including genocide, land loss, and cultural upheaval since the arrival of European settlers. These experiences have left lasting effects on individuals and their cultures, influencing their social, psychological, and physical well-being. There’s a growing interest in understanding how historical traumas like these may be associated with genetic changes, particularly epigenetic changes like DNA methylation. In addition, researchers are exploring how the promotion of cultural preservation within [more…]

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