Impaired Muscle Gene Expression Linked to Type 2 Diabetes

May 25, 2021 Natalie Crowley

Type-2 diabetes comes with a slew of health issues, but one complication that patients often endure is muscle weakness. Poor muscle function makes everyday tasks difficult and reduces activity, which in turn, makes the condition even worse. While exercise and diet can help maintain a patient’s mobility, more information is needed to address the underlying causes that lead to diabetic muscle damage. Scientists at Lund University in Sweden have looked into this matter and have found evidence that one particular [more…]

Switching Off Genes with A New CRISPR Epigenetic Editing Tool

May 11, 2021 Natalie Crowley

CRISPR continues to make headlines as a powerful genomic editing tool. With a Nobel Prize, CRISPR-based COVID-19 diagnostics, and several successful clinical trials in the last year alone, the breakthroughs just keep coming. Now scientists are taking CRISPR to another level – the epigenome.  In a recent paper published in Cell, a team of researchers led by the Whitehead Institute has discovered a unique way to use CRISPR to precisely control gene expression. The new tool is called “CRISPRoff”, and it [more…]

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