Researchers Characterize Chromatin State & Gene Expression Dynamics During Heart Development

November 17, 2020 Natalie Crowley

The human heart is arguably one of the most complex and vital structures of the body. It is also the first organ to develop in a fetus. That’s because it’s needed right away to efficiently transport nutrients and waste throughout the growing embryo. Once formed, the heart will continue to do its same job over the course of one’s life. If the heart does not develop properly, then a person’s health is at great risk. While we know a lot [more…]

Epigenetically Awaking Ancient Parts of Our DNA to Fight Cancer

November 3, 2020 Natalie Crowley

Buried within our DNA, there exists a vast amount of dormant genetic material – a remarkable percentage of which consists of ancient inserted elements that have found their way into our genome, only to be silenced for millions of years.  While the origins of most of these obsolete retroelements are not fully known, their inactive status is epigenetically controlled. It has been suggested that “turning on” these parts of our genome could be useful, especially in fighting off certain diseases [more…]

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