RNA Modification Detected in Swine Coronavirus

October 20, 2020 Natalie Crowley

Years before COVID-19 emerged out of China and entered the US, a lesser-known, highly contagious coronavirus (CoV) had already hit US soil, causing an outbreak of severe diarrhea in pigs. This swine CoV, referred to as porcine epidemic diarrhea virus (PEDV), first appeared in the US in 2013. It caused high mortality and morbidity rates in the pork industry, spreading rapidly throughout the US then further into Canada and Mexico. Although PEDV is not known to be transferable to humans, [more…]

Histone Modifications – Regulators of Viral Infection

October 6, 2020 Mike Spelios

Histones are the most eminent DNA-interacting proteins.  As the primary protein constituent of chromatin, forming complexes with DNA to compact our large genome for efficient nuclear organization, histones support critical cellular processes such as transcription, DNA replication, and DNA repair through diverse post-translational modifications that regulate their interactions with DNA and other nuclear proteins.  Consequently, anomalous changes in histone epigenetics can lead down the road to assorted pathological conditions, making histone modifications and their associated modifying enzymes suitable diagnostic, prognostic, [more…]

WIE-logo-icon

If you like reading our articles…

Join our e-newsletter! Stay up-to-date with our weekly posts on epigenetics and health, nutrition, exercise, and more.