Scientists Solve 30 Year Old Breast Cancer Riddle
Scientists at the Fred Hutchinson Cancer Research Center found that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer. This ground-breaking research helps solve a mystery that has loomed for over 30 years – which gene or genes cause the frequent loss of one copy of chromosome 16 in breast cancer cells. Dr. Gala Flippova, staff scientist at Fred Hutchinson, and his colleagues originally cloned the CTCF gene and mapped [more…]