For The Scientist

Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes

Scientists from Japan developed methylation-specific fluorescence in situ hybridization (MeFISH) for microscopic visualization of DNA methylation status at specific repeat…

12 years ago

Illumina Doubles Output of Benchtop Sequencer MiSeq to 15 Gb

San Diego-based Illumina, Inc. doubles the sequencing output of its benchtop sequencer MiSeq to 15 gigabases (Gb) by increasing the…

12 years ago

Identifying Site Specific Methylation in tRNAs and Target Substrates of RNA Methyltransferase NSun2

Currently, DNA methylation is one of the most broadly studied and well-characterized epigenetic modifications associated with gene silencing. The biological…

12 years ago

System for Optical Control of Mammalian Endogenous Transcription and Epigenetic States

Robust and versatile technologies that enable optical modulation of transcription in the mammalian endogenous genome have been difficult to achieve…

12 years ago