Histone Modifications and Epigenetic Regulation Could Hold the Key to Reversing Aging

September 8, 2015 Bailey Kirkpatrick

Epigenetics has numerous connections to the process of aging, research hinting at the association between longevity and factors such as transcriptome length and DNA methylation patterns. Clearly, understanding the molecular controls of aging proves to be an intriguing endeavor as we try to interpret the clues of how we might slow down and perhaps even reverse aging. Although research has a long way to go before we can expect anything akin to a fountain of youth, studies are offering new [more…]

Computer Algorithm Uses Epigenetics to Identify “Aging Genes”

May 21, 2014 Bailey Kirkpatrick

Restricting calorie consumption without malnutrition has been shown to prolong lifespan in various species, including yeast, worms, flies, monkeys, and humans. Although the underlying mechanism is not yet known, an advanced computer algorithm sheds light on the concept and potential causes. At Tel Aviv University’s Blavatnik School of Computer Science, Keren Yizhak and her colleagues developed something called a genome-scale metabolic model (GSMM), creating a computer algorithm that predicts which genes can be “turned off” to produce the same anti-aging [more…]

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