…Islets of Langerhans. To determine the effect that T2D has on this area, the research team decided to examine DNA methylation patterns in the pancreata of obese mice, as well…
…brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Philip L De Jager et al. August 2014. References: Bringham and Women’s Hospital. DNA Methylation Involved in Alzheimer’s. August 2014….
…identified increased DNA methylation as a result of one night of wakefulness and an alteration in gene expression. DNA methylation is an important epigenetic mechanism known to play a central…
…ants that reinforces the importance of a key epigenetic mechanism, known as DNA methylation, and supports the hypothesis that environmental factors impact the expression of the aforementioned traits as well…
…the tropical environment has suffered as a result of some faulty epigenetic machinery. Researchers utilized bisulfite conversion and microarrays to analyze the methylation of the plant DNA and published their…
…are using AI to develop deep-learning programs to predict single-cell transcription factor binding, drawing from extensive genomic and epigenetic data. In this study, Linköping University researchers harnessed DNA methylation data…
…deficiency. In their study, they focused on an in vitro cell culture system and utilized an aged mouse model to characterize the activation of the immune system and DNA methylation…
…onto DNA at the 5-carbon position of cytosine. DNA methylation was identified by the researchers as one potential explanation for the upregulated gene activity. The researchers found cancer cells over-expressing…
The scientists at Johns Hopkins University used a genome-wide pharmacologic transcriptome approach to identify two novel cancer-specific DNA methylation markers in cultured pancreatic cancer cells: BNC1 and ADAMTS1. Using a…
…age of most tissues and cell types based on DNA methylation that can selectively switch off genes. This age predictor was generated by using data of 8,000 samples from 82…
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