5-methylcytosine is found in the context of paired symmetrical methylation of a CpG site. In normal somatic cells, most CpG…
To form chromatin, DNA is tightly wrapped around nuclear proteins called histones. The repeating DNA-histone complex, which consists of 146…
In human DNA, 5-methylcytosine is found in approximately 1.5% of genomic DNA. In somatic cells, 5-mC occurs almost exclusively in…
Currently, DNA methylation is one of the most broadly studied and well-characterized epigenetic modifications associated with gene silencing. The biological…