Targeting Epigenetics and Metabolism to Prevent Cancer Growth
New research has helped to clear up the function of a well-known tumor suppressor gene, RB, which prevents aberrant cell growth. Researchers from the University of Illinois at Chicago and Universitat Pompeu Fabra in Barcelona have found that pRb, or retinoblastoma protein, is a tumor suppressing protein encoded by RB that maintains proper functioning of a cell’s metabolism. By epigenetically modifying histones, pRb works to control tumor cell growth. The study was published in Genes and Development. Tumor suppressor proteins [more…]
