DNA Methylation and Glucocorticoid Resistance Offers Clues to Improve Cancer Drugs
Scientists from St. Jude Children’s Research Hospital conducted a study that illuminates a mechanism by which leukemia cells resist steroids, a key factor detrimental to the success of chemotherapy. This discovery could help create more effective cancer drugs and improve the treatment of many autoimmune related diseases. The researchers looked at a certain type of steroid hormones involved in the immune system, known as glucocorticoids. These hormones are crucial components to the chemotherapy drug cocktail that has helped increase long-term [more…]
