Histone Modifications
…in cancer cells. HDAC inhibitors are currently being developed as anticancer agents.2 Getting Started the Easy Way Extract your nuclear proteins from your sample of interest, then utilize an ELISA-like…
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The Role of Epigenetics in Traditional Chinese Medicine
…tanshinones, could stop the growth of breast cancer. One specific tanshinone, known as T1, was particularly effective in inhibiting the growth of triple-negative breast cancer cells. The protein Aurora A,…
Simple Blood Test of DNA Methylation Markers Promises Early Diagnosis of Pancreatic Cancer
The scientists at Johns Hopkins University used a genome-wide pharmacologic transcriptome approach to identify two novel cancer-specific DNA methylation markers in cultured pancreatic cancer cells: BNC1 and ADAMTS1. Using a…
A Role for m6A Methylation in the Immune Response of Natural Killer Cells Toward Cancer
…cells, scientists are interested in engineering them to endure and overcome cancer progression. One new area of research that has been increasingly studied in cancer and could provide some answers…
A Glimmer of Hope in the Ugly Face of Addiction: Epigenetics May Help Prevent Relapse
…withdrawal symptoms, and the desire to use again. Previously, it had been studied that an epigenetic drug could alter DNA methylation in the brain during drug withdrawal with hopes in…
Epigenetics: Fundamentals
…genetic and epigenetic errors can transform a normal cell into an invasive or metastatic tumor cell. Cancer. Cancer was the first human disease to be linked to epigenetics. Studies performed…
Epigenetics of Breastfeeding: 4 Diseases and Disorders That Breast Milk Could Protect Against
…might reduce a woman’s risk of breast cancer. It is not very clear yet, but the evidence so far has shown an inverse correlation between breastfeeding duration and breast cancer…
Epigenetic Study Unveils Vital Role of Housekeeping Genetic Elements and Potential for Cancer Therapy
…cancer cells, a subset of HK-CREs exhibited reduced activity across diverse cancer subtypes due to aberrant methylation, notably those linked to zinc finger genes in chromosome 19’s sub-telomere regions. This…
The Epigenetic Marks of Circulating Cell-Free DNA (cfDNA)
…to same cancer type. These findings could be useful for the classification of cancers during early diagnosis, and for a wider group of pathologies. Challenges and limitations Despite the extensive…
Epigenetics Explains Increased Drug Resistance in Malaria Parasite
…issue persists – drug resistance. In recent years, it has become a significant hurdle in the global effort to eradicate malaria. The parasites that contribute to the disease have the…
