…has been used to describe heritable changes in phenotype resulting from environmental factors. Mechanisms altering gene expression include DNA methylation and histone modifications. Chromatin remodeling, or how DNA is packed…
…of open chromatin, DNA-binding proteins, individual nucleosomes and chromatin compaction at nucleotide resolution. By using ATAC-seq, the scientists discovered classes of DNA-binding factors that strictly avoided, could tolerate, or tended…
…switched on or off via molecular tags that attach to DNA and transfer signals to tell the cell how to arrange the DNA. HDAC inhibitors are drugs that lead to…
Researchers rely on high quality antibodies to perform successful chromatin immunoprecipitation (ChIP) experiments. When investigating the protein-DNA interaction of interest, valid and reliable results simply cannot be attained using nonspecific…
…Broad Institute of MIT and Harvard developed light-inducible transcriptional effectors (LITEs) — an optogenetic two-hybrid system integrating the TALE DNA-binding domain with a light-sensitive cryptochrome 2 protein and its partner…
…also called brain plasticity, refers to the changes in neural connections such as synapses and neural pathways as a result of changes in behavior, environmental exposure and neural processes (1,2)….
…harnessing the power of immune cells and related molecular pathways for eliminating cancer, but this and other studies show promise for anti-cancer treatment and open new doors for advancing cancer…
…is involved in mediating response to cocaine use in the NAc. UPS also helps to regulate epigenetic mechanisms like histone modification and DNA methylation. During the first day of abstinence,…
About Us WhatIsEpigenetics.com is a New York-based blog and news aggregator for epigenetics-related subjects, supported and funded by epigenetic biotechnology company EpiGentek. With our writing team and contributors from diverse…
…these findings Author and research lead Leena A. Hilakivi-Clarke, PhD, a professor of oncology at Georgetown Lombardi Comprehensive Cancer Center, is thrilled about the research and its implications for the future….
Copyright © WhatIsEpigenetics.com. All rights reserved | Privacy Policy Advertise | Contact Us | Submit An Article
