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Predicting Schizophrenia Risk Based on Epigenetics

August 31, 2021 Natalie Crowley

Schizophrenia is a complex and severe mental illness that affects approximately 1% of the global population. Often misdiagnosed for symptoms similar to other cognitive disorders, this condition lacks a valid biochemical laboratory test to support its clinical diagnosis. Studies have shown that schizophrenia has both genetic and environmental components, suggesting that epigenetic dysregulation is likely an important contributor to its etiology. Thus, developing a diagnostic tool that can identify these abnormal epigenetic modifications could help detect the disease properly and [more…]

Epigenetic Imbalance Could Lead To Bipolar Disorder, Schizophrenia

August 13, 2019 Tim Barry

The importance of mental health is a prominent and ongoing issue in the United States. According to the National Alliance on Mental Illness, 1 in 5 American adults experiences a mental illness in a given year, which can make living a healthy lifestyle challenging. Some mental illnesses are due to problems with brain chemistry and are not well understood, therefore are severely under-treated. Dopamine—one of our brain’s “feel good” chemicals— is a neurotransmitter in the brain responsible for transporting information [more…]

Epigenetic and Genetic Connections to Schizophrenia in the Developing Brain

December 8, 2015 Bailey Kirkpatrick

Connections between epigenetics and schizophrenia have been previously speculated, although no one knows for certain exactly how epigenetic tags may or may not control the development of the disease. Now, research conducted by a group of international scientists is helping us to understand the epigenetic and genetic components of schizophrenia in the developing human brain. Headed by researchers from the University of Exeter Medical School, Cardiff University and King’s College London, the study was published in Nature Neuroscience and details, [more…]

The Epigenetics of Schizophrenia

December 8, 2014 Adam Alonzi

The nascent field of epigenetics has been helpful in elucidating upon other polygenic traits and diseases. Thus it only seems logical to apply it to the study of , a chronic and debilitating illness with a sundry of risk factors. In his widely cited 2013 article, Dr. Thomas Insel defines schizophrenia as “a collection of signs and symptoms of unknown aetiology, predominantly defined by observed signs of psychosis.” The NIMH estimates it affects 1 out of 100 people. Yet in [more…]

Uncovering the DNA Methylation Profile of Brain Immune Cells

January 18, 2022 Natalie Crowley

We all know by now, especially in the days of COVID-19, how crucial it is to have a properly working immune system. If our bodies can produce the right antibodies and white blood cells to protect us from invading pathogens, we can survive an illness. Sometimes, the body’s immune system is out of whack, doing more damage than good, which is why understanding how immune cells work is essential for developing ways to overcome diseases. Interestingly, the brain and central [more…]

New Method to Understand Two levels of Epigenetic Changes in Tissues

October 22, 2019 Andrea P

More and more people are learning about how an individual’s genetic sequence determines their body’s development and how that also affects their health over a lifetime. But genes alone are not the only factor contributing to the way an individual’s features emerge and perform. Things like how DNA is exposed—or not exposed—to the cellular machinery that carries it from code to reality are also vital to consider. The field of epigenetics is still rather young, and much effort is needed [more…]

Epigenetic Study Finds Overactive Hormone May Drive Hypersexual Disorder

October 15, 2019 Natalie Crowley

Sex is a natural and normal part of life. When practiced safely with a consenting partner, it’s not only pleasurable but has certain health benefits. However, some people can be obsessed with sex, to the point that it causes them more harm than does any good. These individuals are usually diagnosed with having hypersexual disorder (HSD) – a condition where excessive sexual thoughts and actions interfere with the ability to function day-to-day. Often accompanied by other medical conditions, the causes [more…]

Your Zodiac Sign and Epigenetics

September 3, 2019 Natalie Crowley

Do you know your zodiac sign and what it means? If you do, perhaps you have the qualities that are typically predicted for people under that sign. According to astrologers, your zodiac sign, which refers to the position of the stars on the date you were born, can strongly influence your personality and life. But how can something so far away, like the stars or any other celestial object, control one’s behavior or predict occurrences? Well, there’s no scientific evidence [more…]

What is Paleoepigenetics?

April 30, 2019 Hayley Mann

To unravel the complexities surrounding the genome, advanced technologies in genomics and epigenetics are typically necessary. Most of these tests and instruments are designed with high-quality DNA and tissue specimens in mind. Accordingly, scientists preferentially use concentrated and freshly extracted DNA to achieve the best results. Yet, some researchers do not have the luxury of working with modern DNA. This is why the field of ancient DNA (aDNA) emerged. Evolutionary biologists and anthropologists that study humans and other organisms from [more…]

Epigenetic Marks on DNA May Indicate Breast Cancer Risks

October 9, 2018 Lisa Fox

It’s hard not to know someone who has been affected by breast cancer. Nearly one in eight women will battle this disease in her lifetime and for those women affected it becomes the battle for their life. Early detection and medical advances stem the tide of this disease, but each study brings us a little closer to unlocking ways to combat it. While women (and men) with a family history are at higher risk for developing breast cancer, a recent [more…]

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