Epigenetics Explains Increased Drug Resistance in Malaria Parasite

March 18, 2019 Natalie Crowley

Malaria is a serious, sometimes fatal disease that is caused by a single-cell parasite and transferred to humans by the bite of a mosquito. Each year, millions of cases of the illness are reported, predominantly in young children and pregnant women from the sub-Saharan African region. Although deadly, malaria is preventable and treatable if tackled early enough. However, one hindering issue persists – drug resistance. In recent years, it has become a significant hurdle in the global effort to eradicate [more…]

Mouse Study Verifies Gene’s Role in Autism Via Epigenetics

March 12, 2019 Natalie Crowley

More families are living with autism today than ever before. It’s a common diagnosis with a prevalence of 1 in 59 children in the US. Despite all the efforts to understand this condition, there is still no known cause. The consensus among researchers is that autism is predominantly genetic with a few environmental factors involved. However, determining a heritable link here is complex since any number of genotypic variations could underlie autism. To better pinpoint genes that may contribute to [more…]

High Fat Diet in Fruit Flies Links Epigenetics to Inherited Heart Disease

March 5, 2019 Tim Barry

In the United States, obesity has become an epidemic that has been sweeping the nation for quite some time. Poor dietary habits have become far too customary among the American people, so it is no surprise that obesity rates are extremely high. Obesity presents a person with numerous adverse health effects that can shorten life expectancy like hypertension, diabetes, and perhaps most importantly, heart disease. Heart disease is currently the leading cause of death in both men and women in [more…]

Intended Epigenetic Drug Has Opposite Effect for Lung Cancer

February 26, 2019 WhatIsEpigenetics

Cancer is a complex disease influenced by numerous factors including genetic make-up, lifestyle, and the environment. Over the years, the growing field of epigenetics has greatly contributed to our understanding of cancer and tumor progression. It has also led to the development of novel drug therapies. Yet, despite the fact that epigenetic regulators have become attractive anticancer targets, many scientists believe that extra caution should be taken when assessing their overall effects. In a new study, one potential epigenetic therapy [more…]

Epigenetic Test Beats Pap & HPV for Detecting Cervical Cancer

February 5, 2019 Natalie Crowley

Cervical cancer used to be the number one cause of death in women about a hundred years ago. But thanks to advancements in medical science, this disease is almost preventable today. However, cervical cancer (CC) still claims the lives of over 4,000 women each year in the US. While Pap and human papillomavirus (HPV) testing have significantly contributed to the lower mortality rates, there are still certain types of CC that are not easily detected. Now, a new technique has [more…]

Heat Stress Upsets the Epigenome of Dairy Cattle Offspring

January 29, 2019 Amanda Conroy

If you are familiar with cattle, you may be aware of the dangers heat poses to these sensitive creatures. They have a lower tolerance for heat than humans do, and if their bodies become too warm, they can experience changes that are neither beneficial for farmers and consumers, nor for the animals themselves. Temperature, precipitation, humidity, wind, and amount of direct sunlight are all main factors in determining an animal’s body temperature. If these variables are not monitored properly, cattle [more…]

Marijuana Use May Epigenetically Impact Sperm Health

January 22, 2019 Tim Barry

Marijuana has been the topic of much recent debate across the United States, and its legalization has undoubtedly gained some ground. Almost all states in the US have legalized marijuana in some capacity, whether it be for medicinal or recreational purposes which could have a positive effect on both medicine and the economy. Cannabis has provided some relief for patients suffering from various sicknesses like chronic pain, depression, PTSD, anxiety, and even HIV/AIDs and cancers. As the use of marijuana [more…]

Scientists Develop a New RNA Sequencing Approach to Advance Our Understanding of the Human Microbiome

January 8, 2019 Natalie Crowley

The human body is made up of about 100 trillion cells, but not all these cells are ‘real’ human cells. About one-tenth, in fact, are tiny organisms like bacteria, fungi, and viruses that live within us and on us. These organisms are collectively known as microbes and they play an essential role in human health and disease. Yet, exactly how they function and are affected by environmental changes is not entirely understood, and even less is known about how the [more…]

A Fatty Diet May Affect Behavior Across Generations Through Epigenetic Mechanisms

December 26, 2018 James Cain

Having a high-fat diet (HFD) is not only linked to obesity but also to an increased risk of developing heart disease, type 2 diabetes, and certain mental health disorders. With obesity levels on the rise, it’s critical that we know more about how a HFD affects the body and find ways for early prevention. In recent years, there has been a growing area of interest into the behavioral consequences of a HFD and if these are passed onto subsequent generations [more…]

Selective Survival In The Womb Based On Random Epigenetic Variation May Explain Adult Health Problems

December 18, 2018 Natalie Crowley

It’s been said before that health begins in the womb. That’s because the conditions we encounter in utero impact not only our well-being in infancy but throughout our entire lives. But what happens when the nutritional environment in the womb is less than favorable? Most epigenetic studies have suggested that embryos respond to adverse environmental conditions by adjusting their gene expression. However, new research proposes something entirely different may occur. Instead of adapting to the environment, random variations in gene [more…]

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