Common Flame Retardant Alters the Epigenome of Aquatic Organisms

April 16, 2024 Natalie Crowley

Flame retardants are ubiquitous chemicals added to numerous consumer products to prevent the spread of fire. While they are essential in enhancing fire safety, their widespread use has raised concerns about their environmental and health impacts. One such flame retardant, triphenyl phosphate (TPhP), has gained popularity as an alternative to previously restricted compounds. However, recent studies suggest that TPhP may pose risks to both aquatic ecosystems and human health through its potential to disrupt endocrine systems and alter gene expression. [more…]

Epigenetic Changes in Immune Cells Linked to Alzheimer’s Disease

April 2, 2024 Natalie Crowley

Alzheimer’s disease is a degenerative brain disorder that impacts millions globally. While the exact cause of the disease is still unknown, a recent study by Northwestern University (NU) has shed light on the potential role of epigenetic modifications in the immune system of Alzheimer’s patients. The study found that Alzheimer’s patients experience epigenetic changes in their blood’s immune system, which could be influenced by environmental factors, past infections, and lifestyle behaviors. These findings could pave the way for the development [more…]

DNA Methylation’s Role in Preventing Cleft Lip and Palate

March 5, 2024 Natalie Crowley

Cleft lip and palate stand out as the most prevalent craniofacial birth anomalies worldwide, affecting approximately 1 in 700 newborns. Despite extensive research spanning decades, the precise etiology of most cases remains elusive, as does effective preventive measures. Understanding the causes of this abnormality has mainly focused on genetic factors, revealing numerous risk loci along the DNA, although direct causative variants are rare. Therefore, it is thought that this defect arises from a mix of genetic and environmental factors. Yet, [more…]

Scientists Use Machine Learning to Develop an Epigenetic Clock for Predicting Biological Age Better

February 20, 2024 Natalie Crowley

In the quest to unravel the mysteries of aging, scientists have long turned to our genetic code for answers. While machine learning models have offered insights into predicting biological age, understanding the causal factors behind aging has yet to be discovered. However, a groundbreaking study has now shed light on the hidden workings of aging by delving deep into the intricate realm of epigenetics. Scientists at Brigham and Women’s Hospital, part of Mass General Brigham, have developed an innovative “epigenetic [more…]

Type 2 Diabetes Linked with Epigenetic Changes

February 6, 2024 Elizabeth Fontanilles

Diabetes is a widespread health issue that affects millions of people worldwide. The disease is complex and can develop due to a combination of genetic and lifestyle factors. Given its increasing prevalence, scientists worldwide are investigating the underlying genetic complexities and epigenetic factors of diabetes in more detail. One question that researchers are interested in is whether epigenetic changes cause type 2 diabetes or if the changes occur only after a person has become ill. A new study by Lund [more…]

Positive Parenting May Reverse Epigenetic Age in Children Affected by Adversity

January 23, 2024 Natalie Crowley

Growing up amid adversity, encompassing elements like poverty, child maltreatment, and community violence, not only poses a significant risk for psychopathology and lifelong health challenges but also has been shown to accelerate the biological or epigenetic aging process in children. However, a new study featuring research conducted in the lab of Professor Justin Parent, an assistant professor of psychology at the University of Rhode Island, has introduced a promising prospect. Positive parenting interventions might hold the key to slowing down [more…]

Epigenetic Study Unveils Vital Role of Housekeeping Genetic Elements and Potential for Cancer Therapy

January 9, 2024 Natalie Crowley

Advancements in technology have opened doors for scientists to delve deep into the complex world of genetic control elements, unveiling the intricate mechanisms governing gene activation within our genetic code. Contrary to the simplistic perception of cis-regulatory elements (CREs) as mere genetic on/off switches, emerging evidence underscores their capacity for nuanced behaviors. They’re not just toggles for gene enhancement; they orchestrate complex functions pivotal to sustaining cellular health. New research originating from Japan has uncovered about 11,000 significant genetic switches, [more…]

The Epigenetic Impact of Cannabis Use During Pregnancy on Child’s Health

August 8, 2023 Natalie Crowley

In recent years, the popularity and availability of cannabis has grown significantly, with various consumption methods like edibles gaining traction. However, alongside this trend, there has been a worrisome increase in cannabis use among pregnant women. Unfortunately, our understanding of the detailed effects of using cannabis during pregnancy on the developing child remains limited. Because normal fetal development relies on the crucial process of epigenetic regulation and gene expression modification, it has been suggested that studying the molecular changes linked [more…]

New Epigenetic Method Detects Differences in Animal Farming Practices

May 16, 2023 Natalie Crowley

In today’s world, there is an increased emphasis on eating healthy and being environmentally friendly. One of the key factors in achieving these goals is the source of the food we eat. Consumers are now more conscious of where their food comes from and want to be sure that it is grown in an environment free of harsh chemicals that supports health. But how can we be sure that the food we’re eating comes from an organic or free-range farm? [more…]

Mom’s Behavior May Leave a Lasting Mark on Her Child’s Genes

May 2, 2023 Natalie Crowley

From the moment a child is born, a mother’s love and care are crucial for their physical and mental development, especially during the critical early stages of infancy. The environment and experiences children encounter during these formative years can have a lasting impact on their biology and health, even influencing future generations. Recently, a study out of Washington State University (WSU) has added to our understanding of the crucial role played by mothers. The study found that a mother’s behavior [more…]

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