Demethylating Agent May Boost Chemotherapy Effectiveness for Specific Type of Childhood Leukemia

January 16, 2017 Natalie Crowley

Fifty years ago, a child diagnosed with acute lymphoblastic leukemia (ALL), the most common type of pediatric cancer, had little to no chance of survival. Today, those odds have increased dramatically thanks to tremendous advances in chemotherapy and other treatments. Cure rates for this type of leukemia can reach as high as 90 percent. Yet, there is one subgroup of pediatric ALL that is still very therapy resistant, T-Acute Lymphoblastic Leukemia (T-ALL). T-ALL is an uncommon, though aggressive, subclass of [more…]

Book Review: Super Genes

April 13, 2016 Natalie Crowley

Change your genes, change your life. Seems like a radical idea, especially since we’ve been taught to believe that our genes are set in stone when we are born. Not so, according to the authors of Super Genes, Deepak Chopra, M.D. and Rudolph Tanzi, Ph.D. It seems that we are not at the mercy of our genes, rather we are the “user and controller” of them. And, through simple lifestyle changes, we may be able to modify our gene activity [more…]

The Epigenetics Behind the Flu

November 17, 2015 Natalie Crowley

When the flu hits, it typically hits hard and fast. At first, you might only notice a slight cough and some sniffles and then, before you know it, you’re unable to get out of bed. The fever, sore throat, chills, muscle aches, and overall exhaustion take over your body and you’re done for — at least for a few days, if you’re lucky. Influenza (aka “the flu”) is a dreadful virus that’s seriously contagious and seemingly unavoidable for some. In [more…]

A Review of the Epigenetics Course: Epigenetic Control of Gene Expression

October 6, 2015 Natalie Crowley

Perhaps it’s just the American in me, but why does everything seem more appealing when told in an Australian accent? Ok, that wasn’t entirely the reason why I stuck it out for nearly eight weeks to take an online course about epigenetics offered by the University of Melbourne. The truth is, it was interesting, I learned a lot, and despite the fact that it crept into my summer free time, I actually liked it. I’ve never taken any online course, [more…]

Could Epigenetics Help Feed the World?

July 14, 2015 Natalie Crowley

If you were a teenager in 1985, like I was, you probably remember spending an entire day in July plopped in front of the TV watching one of the greatest concerts of all time – Live Aid. The legendary concert broadcast-live around the world that featured an amazing line-up of rock stars was, and still is, the most successful charity event ever held. But, let us not forget its purpose – to raise money and awareness for the famine that [more…]

Could Epigenetics Explain the Origins of Allergic Disease?

March 24, 2015 Natalie Crowley

Finally, spring is here – that wonderful time of year when the temperature starts to rise and everything is in bloom. But for many of us, it also marks the beginning of allergy season. That means itchy watery eyes, sneezing, running nose, coughing and overall misery. But allergies don’t just affect people in the spring and they are not all related to weather. According to the Centers for Disease Control and Prevention (1), more than 50 million Americans have an allergy [more…]