April 2020 | What is Epigenetics?

Epigenetic Marks May Regulate Liver Disease

April 21, 2020 Brandon Eudy

Nonalcoholic fatty liver disease (NAFLD) is an increasingly alarming health problem in the United States where it is estimated that up to 30% of the population has a fatty liver. Approximately 10% of NAFLD patients will progress in disease severity leading to inflammation and fibrosis and eventually more serious consequences such as cirrhosis or liver cancer. Better understanding the molecular and epigenetic changes in the liver driving disease progression could lead to better treatments. Understanding how DNA methylation is altered [more…]

Epigenetic Marker in Blood May Help Detect Alzheimer’s

April 14, 2020 Andrea P

According to the Alzheimer’s Association, 47 million people worldwide are living with Alzheimer’s. But since it can take 20 years for brain changes to accumulate into the symptoms that lead to diagnosis, effective intervention can be difficult. Even diagnosis itself poses a challenge, with only one out of every four people suffering from Alzheimer’s actually receiving a diagnosis. This is why scientists have been looking to find anything they can leverage to help pinpoint which patients are more likely to have [more…]

Insight Into the Inheritance of Epigenetic Marks

April 3, 2020 Andrea P

An individual’s DNA contains the sequence of nucleotide bases that provide instructions for how every cell in their body is to develop and differentiate. When DNA is read, its instructions are followed to guide the development of cells, allowing genes to be “expressed”. Scientists are actively working to map out the cellular signaling pathways that determine how DNA is differentially expressed, as well as the things that could go wrong, which could ultimately end up in disease. But there’s an added [more…]

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