September 2016 | What is Epigenetics?

Age and exercise impacts epigenetic mechanisms

Can Your Age Influence the Epigenetic Effects of Exercise?

September 27, 2016 Bailey Kirkpatrick

We all know the extensive benefits of exercise: work out to stave off disease, improve mental acuity, lose weight, reduce stress, and so on. But even with all these benefits, there are still some questions surrounding the molecular causes that underlie them. Epigenetics has been particularly helpful in gaining new insights into the wide range of health benefits of exercise. Recently, a study showed that exercise could epigenetically keep the brain healthy by boosting the production of a protein called [more…]

RNA Methylation Gives Epigenetic Clues to Strengthening Memory

September 20, 2016 Bailey Kirkpatrick

Memory is a complex process, one that we have only just begun to understand. Research hints that it might be possible for histone modification to degrade memory if we don’t get enough sleep or that certain epigenetic anti-cancer drugs known as HDAC inhibitors could sharpen memory. RNA methylation is an epigenetic mechanism that has been recently gained a lot of attention in the field of epigenetics. Now, scientists have discovered that the epigenetic mark found on RNA, called m6A, or [more…]

The Epigenetic Marks of Circulating Cell-Free DNA (cfDNA)

September 16, 2016 Blanca Valle

Circulating cell-free DNA (cfDNA) are small DNA fragments found circulating in plasma or serum, as well as other bodily fluids. The cfDNA isolated from plasma usually contains fragments of about ~170-500 bp, mostly corresponding to ~170 bp mononucleosomal and ~300 bp dinucleosomal DNA fragments [1,2], thought to arise mostly from apoptotic cells. In addition, larger fragments (>1,000 bp) are often detected, thought to arise mostly from necrotic cells. In healthy individuals, the levels of cfDNA in plasma/serum are generally low, ranging between [more…]

menopause may epigenetically speed up aging

Menopause and Insomnia Might Epigenetically Speed Up Aging

September 13, 2016 Bailey Kirkpatrick

For years, scientists have disagreed on whether menopause causes aging or aging leads to menopause, giving rise to a “which came first” debate. New epigenetic research may help settle this long-standing disagreement, offering evidence that menopause might actually make a woman age faster. Two recent UCLA studies show that menopause and its common side effect – insomnia – may accelerate aging. This could potentially increase a woman’s risk for diseases related to aging and possibly lead to an earlier death. [more…]

Epigenetics Could Turn on ‘Obesity Switch’

Epigenetics Could Turn on an ‘Obesity Switch’

September 6, 2016 Bailey Kirkpatrick

We know that a predisposition to become overweight is found in our genes. Now, we’re starting to learn that epigenetics also has a hand in determining whether a person will become fat or lean. New research is uncovering the possibility of an epigenetic switch that is, interestingly, either “on” or “off”. A group of researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg published their study in Cell. More than one-third of individuals are considered to be [more…]

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