Smoking Linked to Epigenetic Warning Signs of Cancer in Cheek Cells

May 26, 2015 Bailey Kirkpatrick

New research published in JAMA Oncology shows that DNA damage that occurs as a result of smoking may be found in cheek swabs. In light of this research, smoking is thought to adjust the epigenetic profile of cheek cells and the resulting epigenetic landscape may even be used as an early warning sign of other cancers typically unrelated to smoking, such as gynecological and breast cancers. Professor Martin Widschwendter, Head of the Department of Women’s Cancer at the UCL Institute [more…]

3 Epigenetic Reasons to Meditate Your Stress Away

May 19, 2015 Bailey Kirkpatrick

Feeling stressed? You’re not alone. According to the American Psychological Association, people are living with stress at levels higher than what is considered healthy. Unsurprisingly, the APA found the top four sources of stress to be money, work, family responsibilities, and health concerns. Are you nervous about that project that’s due this week? Worried about the last of your sample that’s incubating in the lab? Perhaps you’re just convinced money is some sort of mythical object that you might one [more…]

DNA Methylation and Glucocorticoid Resistance Offers Clues to Improve Cancer Drugs

May 12, 2015 Bailey Kirkpatrick

Scientists from St. Jude Children’s Research Hospital conducted a study that illuminates a mechanism by which leukemia cells resist steroids, a key factor detrimental to the success of chemotherapy. This discovery could help create more effective cancer drugs and improve the treatment of many autoimmune related diseases. The researchers looked at a certain type of steroid hormones involved in the immune system, known as glucocorticoids. These hormones are crucial components to the chemotherapy drug cocktail that has helped increase long-term [more…]

Can An Infection Alter Your Epigenome?

May 5, 2015 Bill Sullivan

There are many examples of infectious agents that are capable of modifying the behavior of their host organism. Pathogens typically co-opt their host in ways that create an opportunity to spread into another host. For example, the rabies virus is transmitted through saliva, so the virus transforms its host into an unusually aggressive beast that is prone to bite other animals. The single-celled parasite known as Toxoplasma gondii is another clever puppeteer of its host. Rodents infected with this microbe [more…]

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